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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2020, Vol. 14 ›› Issue (04): 427-429. doi: 10.3877/cma.j.issn.1674-3946.2020.04.031

Special Issue:

• Original Article • Previous Articles     Next Articles

Analysis of survival status of patients with laparoscopic surgery for cholangiocarcinoma

Zhanyang He1,(), Xuexiang Ying2, Qiuhong Fan1, Haide Gao1, Xiaofeng Yu1   

  1. 1. People’s Hospital of Suzhou High-tech Zone 215010, China
    2. Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiaotong University 200233, China
  • Received:2019-07-01 Online:2020-08-26 Published:2020-08-26
  • Contact: Zhanyang He
  • About author:
    Corresponding author: He Zhanyang, Email:

Abstract:

Objective

To explore the short-term and long-term survival status of patients with laparoscopic surgery for cholangiocarcinoma.

Methods

A clinical data of 96 patients with cholangiocarcinoma treated in our hospital from January 2012 to January 2014 were divided into two groups according to the different surgical methods. The drainage group was treated with hepatic biliary drainage and the operation group was treated with laparoscopic radical operation. Statistical analysis was performed using SPSS 23.0 software. The t test was used to compare the two groups of measurement data. Postoperative complications and short-term efficacy were compared using chi-square test (conventional data) and rank sum test (grade data). The survival analysis model was the Kaplan-Meier product limit model, and the survival rate of the two groups was compared with the Logrank test, and P<0.05 was considered statistically significant.

Results

There were 10 cases of complete remissions in the drainage group and 21cases of partial remissions. There were 17 cases of complete remission in the operation group and 27 cases of partial remission. The total effective rate of the short-term effect in the operation group was 91.7%, which was significantly higher than the total effective rate of the drainage group with 64.6% (P<0.05). The postoperative complication rate was 6.3% in the operation group, which was significantly lower than that in the drainage group of 29.2% (P<0.05). The 1-year survival rate in the drainage group was 39.6%, the 3-year survival rate was 14.6%, and the 5-year survival rate was 10.4%. The 1-year survival rate in the surgery group was 60.4%, the 3-year survival rate was 22.9%, and the 5-year survival rate was 16.7%. The postoperative survival rates between the two groups was statistically significant (P<0.05).

Conclusion

The short-term curative effect of laparoscopic surgery for cholangiocarcinoma is significantly better than that of transhepatic biliary drainage. The postoperative complications are less and the long-term survival rate is higher, which is suitable for clinical application.

Key words: Bile duct neoplasms, Laparoscopes, Postoperative complications, Survival analysis, Comparative effectiveness research

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