An effectiveness study on the value of ultrasound guided core needle biopsy for the diagnosis of thyroid nodules

doi:10.3877/cma.j.issn.1674-3946.2019.01.022

Abstract

Abstract:

Objective

To evaluate the effectiveness of ultrasound guided core needle biopsy (CNB) for the diagnosis of thyroid nodules.

Methods

From June 2009 to June 2016, 2286 thyroid nodules from 2051 patients undergoing ultrasound guided CNB (US-CNB) in our department and 530 nodules undergoing surgical operation were included in this study. Final diagnosis was confirmed by surgical pathological results. The data were analyzed using SPSS19.0 software. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were calculated, and ROC curve was used to compare the CNB and the surgical pathological results.

Results

The biopsy samples were successfully obtained from 2284 nodules (2284/2286), and the inconclusive result occurred in 2 nodules (2/2286). The sensitivity, specificity, PPV, NPV and accuracy of US-CNB in the 530 nodules were 99.8%, 86.5%, 98.6%, 97.8%, and 98.5%, respectively.

Conclusion

US-CNB has high success rates and diagnostic accuracy; therefore, it is a useful tool for the preoperative diagnosis of thyroid nodules.

Key words: Thyroid nodule, Ultrasonography, interventional, Biopsy, needle, Validation studies

Wenbo Wan, Wei Wang, Changhong Xia, Yukun Luo. An effectiveness study on the value of ultrasound guided core needle biopsy for the diagnosis of thyroid nodules[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2019, 13(01): 69-72.

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Figures/Tables 5

References 16

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CNB病理诊断结果		结节数目	术后病理结果	结节数目
明确恶性结节		?	?	?
?	乳头状癌	411	乳头状癌	411
?	髓样癌	5	髓样癌	5
?	未分化癌	3	未分化癌	3
?	淋巴瘤	1	淋巴瘤	1
恶性可能性大		42	乳头状癌	42
恶性不除外		22	乳头状癌	14
?	?	?	滤泡癌	1
?	?	?	结节性甲状腺肿	5
?	?	?	结甲出血囊肿并纤维化	1
?	?	?	桥本氏甲状腺炎	1
排除恶性		11	滤泡癌	1
?	?	?	结节性甲状腺肿	8
?	?	?	结甲出血囊肿并纤维化	1
?	?	?	桥本氏甲状腺炎	1
明确良性结节		?	?	?
?	结节性甲状腺肿	26	结节性甲状腺肿	26
?	结甲出血囊肿并纤维化	4	结甲出血囊肿并纤维化	4
?	桥本氏甲状腺炎	5	桥本氏甲状腺炎	5

CNB病理诊断结果		结节数目	术后病理结果	结节数目
明确恶性结节		?	?	?
?	乳头状癌	411	乳头状癌	411
?	髓样癌	5	髓样癌	5
?	未分化癌	3	未分化癌	3
?	淋巴瘤	1	淋巴瘤	1
恶性可能性大		42	乳头状癌	42
恶性不除外		22	乳头状癌	14
?	?	?	滤泡癌	1
?	?	?	结节性甲状腺肿	5
?	?	?	结甲出血囊肿并纤维化	1
?	?	?	桥本氏甲状腺炎	1
排除恶性		11	滤泡癌	1
?	?	?	结节性甲状腺肿	8
?	?	?	结甲出血囊肿并纤维化	1
?	?	?	桥本氏甲状腺炎	1
明确良性结节		?	?	?
?	结节性甲状腺肿	26	结节性甲状腺肿	26
?	结甲出血囊肿并纤维化	4	结甲出血囊肿并纤维化	4
?	桥本氏甲状腺炎	5	桥本氏甲状腺炎	5

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