To explore the effect of splenectomy and pericardial devascularization in the treatment of elderly primary liver cancer combined with portal hypertension.

A retrospective analysis of clinical data of 76 cases of elderly primary liver cancer combined with portal hypertension patients in our hospital from January 2014 to June 2017 was made. According to whether undergoing splenectomy and pericardial devascularization, the patients were divided into the control group (undergoing simple hepatectomy, 37 cases) and the observation group (undergoing splenectomy and pericardial devascularization, 39 cases). All data were analyzed by SPSS 20.0 statistical software. The intraoperative and postoperative related indicators were presented as (±s) and examined by t test. The incidence of postoperative complications and survival rates 1, 2, 3 years after surgery were compared by chi square test. P<0.05 indicated that the difference was statistically significant.

Compared with the control group, the operative time in the observation group was significantly extended, the intraoperative blood loss significantly was increased, the incidence rate of postoperative infection, gastrointestinal bleeding and totally postoperative complications significantly were decreased, all above had statistical difference (P<0.05). There was no statistical difference in the bowel function recovery time, drainage tube pull-out time, hospitalization time between the two groups (P>0.05). After surgery, the level of ALB in the two groups were significantly increased, while the levels of ALT and TBIL were significantly decreased, which in the observation group were significantly better than those in the control group, all above had statistical difference (P<0.05). The 1-, 2-, and 3-year survival rates the observation group (87.2%, 71.8%, 53.9%) was respectively higher than the control group (64.9%, 48.7%, 29.7%), all above had statistical difference (P<0.05).

Simultaneous hepatectomy combined with splenectomy and pericardial devascularization in the treatment of elderly primary liver cancer combined with portal hypertension is safe and effective.