To investigate the safety and feasibility of laparoscopic combined endoscopy in the treatment of gastric myogenic stromal tumors (GSTs).

130 patients with GSTs originated from muscularis propria layer treated in our hospital from July 2014 to October 2016 were analyzed, and were divided into laparoscopic surgery group (87 cases) and open surgery group (43 cases) according to surgery methods, and were divided into wedge gastrectomy group (68 cases in laparoscopic group and 20 cases in laparotomy group) and proximal / distal gastrectomy group (19 cases in laparoscopic group and 23 cases in laparotomy group). Laparoscopic surgery group was treated with laparoscopy combined with gastroscope if needed. SPSS 21.0 software was used for data analysis. The intraoperative and postoperative data were described by (±s) and compared with independent sample t test. The incidence of complications, postoperative recurrence or metastasis were compared with χ² test, P<0.05 meant the difference was statistically significant.

There was no significant difference in tumor diameter, mitotic number, grade of malignant potential, serious postoperative complication rate, recurrence or metastasis between the two groups (P>0.05). The length of incision, blood loss , postoperative anal exhaust time and postoperative hospital stay in the laparoscopic surgery group were significantly lower than those in the open group (P<0.05). In the wedge gastrectomy group, the operation time of laparoscopic group was significantly shorter than that of laparotomy group (P<0.05), but there was no significant difference in operation time between laparoscopic group and open laparotomy group with proximal and distal gastrectomy (P>0.05).

It has small trauma, less intraoperative blood loss and rapid postoperative recovery Laparoscopy combined with gastroscopy in Treatment of Gastric Stromal Tumors Originating from Muscularis Propria in patients with gastric stromal tumors originated from muscularis propria treated by laparoscopy combined with gastroscopy, with safe and feasible surgery. It is worthy of clinical application.