To explore the application effect of modified pancreatic duct-jejunum bridge-type internal drainage in laparoscopic pancreaticoduodenectomy (LPD).

This study adopted a prospective design, enrolling 95 patients who underwent LPD from January 2021 to May 2023. Patients were divided into two groups using a random number table: 48 cases in the modified group received modified pancreatic duct-jejunum bridge-type internal drainage, and 47 cases in the control group underwent traditional pancreatic duct-jejunum mucosa anastomosis (including internal drainage). Measurement data such as intraoperative blood loss, operation time, and hospital stay were expressed as (±s), and compared between groups using independent sample t tests. Ranked data or enumeration data (e.g., total incidence of postoperative complications, Clavien-Dindo complication grading) were expressed as rates, and compared using the Rank Sum test or χ² test. Survival analysis curves were drawn by Kaplan-Meier, and survival differences between groups were compared by Log-Rank test.

There were no significant differences in intraoperative blood transfusion volume or hospitalization costs between the two groups (P>0.05). The cumulative overall survival rates showed no significant difference between the modified group and the control group (100.0% vs. 95.7%, Log-Rank χ²=1.887, P>0.05). Compared with the control group, the modified group had less intraoperative blood loss, shorter operation time, drainage tube indwelling time, anastomosis time, and hospital stay, as well as lower amylase levels in drainage fluid on the 1st postoperative day (all P<0.05). The total incidence of postoperative complications and Clavien-Dindo gradeⅠ-Ⅲcomplications in the modified group were lower than those in the control group (4.2% vs. 27.7%, P<0.05). The incidence of B/C-grade CR-POPF in the modified group was 2.1% (1/48), significantly lower than 17.0% (8/47) in the control group (P<0.05).

In LPD, modified pancreatic duct-jejunum bridge-type internal drainage optimizes anastomosis operations, shortens operation, anastomosis, and hospital stay durations, reduces intraoperative bleeding, and has a lower risk of postoperative complications. It is safer and more efficient than traditional pancreatic duct-jejunum mucosa anastomosis (including internal drainage).