A new era of small bowel transplantation：Both achievements and challenges

doi:10.3877/cma.j.issn.1674-3946.2022.06.031

Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2022, Vol. 16 ›› Issue (06): 703-706. doi: 10.3877/cma.j.issn.1674-3946.2022.06.031

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A new era of small bowel transplantation：Both achievements and challenges

Cheng Zhou¹, Ye Yuan¹, Peng Zhang², Ming Cai², Junhua Chen², Yuping Yin², Wei Li², Fan Xiang², Gang Li², Kaixiong Tao², Zheng Wang², Guobin Wang³^,^†()

^1. Department of Gastrointestinal Surgery，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China; Research Center for Tissue Engineering and Regenerative Medicine，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China
^2. Department of Gastrointestinal Surgery，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China; Minimally Invasive Surgery Center，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China
^3. Department of Gastrointestinal Surgery，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China; Research Center for Tissue Engineering and Regenerative Medicine，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China; Minimally Invasive Surgery Center，Union Hospital，Tongji Medical College，Huazhong University of Science and Technology，Wuhan Hubei Province 430022，China

Received:2021-11-29 Online:2022-12-26 Published:2022-10-26
Contact: Guobin Wang
Supported by:
The Major Scientific and Technological Innovation Projects of Hubei Province(2018ACA136)

Abstract

Abstract:

Total parenteral nutrition is an important treatment for intestinal failure，but long-term parenteral nutrition will lead to a series of serious complications，which seriously threaten the survival of patients. Small bowel transplantation provides a new treatment for patients with intestinal failure，which can not only restore clinical autonomic nutrition，but also avoid complications related to parenteral nutrition. In recent years，the development and application of immunosuppressants in small bowel transplantation，and the improvement of surgical techniques and postoperative management have significantly improved the short-term survival rate of patients. Small bowel transplantation has become the standard treatment for patients with intestinal failure. However，small bowel transplantation still faces many challenges：the diagnosis and treatment of immune rejection，prevention and treatment of infection，postoperative nutritional support are still urgent problems to be solved，which seriously affect the long-term prognosis of patients.

Key words: Intestinal transplantation, Intestinal failure, Rejection, Infection, Nutritional support

Cheng Zhou, Ye Yuan, Peng Zhang, Ming Cai, Junhua Chen, Yuping Yin, Wei Li, Fan Xiang, Gang Li, Kaixiong Tao, Zheng Wang, Guobin Wang. A new era of small bowel transplantation：Both achievements and challenges[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2022, 16(06): 703-706.

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