To compare the short-term and long-term effects of laparoscopic-assisted total gastrectomy（LATG）and proximal gastrectomy（LAPG）in the treatment of SiewertⅡesophagogastric junction adenocarcinoma（AEG）.

Clinical data of 90 patients with SiewertⅡAEG from January 2014 to May 2016 were prospectively included. The patients were divided into two groups by random number table method：LAPG group and LATG group，with 45 patients in each group. LAPG group：Laparoscopic assisted proximal gastrectomy，LATG group：Laparoscopic assisted total gastrectomy. The data were processed by SPSS 22.0 software. Perioperative，nutritional status indicators and other measurement data were represented by（

The operation time and lymph nodes dissection in LATG group were significantly higher than those in LAPG group，and the first exhaust time，first feeding time and postoperative hospitalization time were significantly lower than those in LAPG group，with statistical significance（P<0.05）.The incidence of postoperative reflux esophagitis in the LATG group was significantly lower than that in the LAPG group（6.7% vs. 22.2%，P<0.05）.There was no significant difference in Serum hemoglobin（Hb），total protein（TP），albumin（ALB）and other nutritional indexes between 2 groups 1 year after operation（P>0.05）.The median follow-up was 72 months.Kaplan-Meier analysis showed that the 5-year overall survival rate of LATG group was 51.1%，and the disease-free survival rate was 42.2%；The 5-year overall survival rate and disease-free survival rate of LATG group was 37.8% and 24.4%.There was significant difference in 5-year overall survival rate and disease-free survival rate between 2 groups（P<0.05）.

Compared with LAPG，LATG treatment of SiewertⅡ AEG not only benefits postoperative recovery，reduces postoperative reflux esophagitis，does not increase the risk of surgery and malnutrition，but also have more thorough lymph node dissection and better long-term results.