To investigate the clinical effect of modified through pancreaticojejunostomy in pancreaticoduodenectomy（PD）after “G” shape shaped path resection.

The clinical data of 80 cases of PD with “G” shaped surgical path from November 2018 to August 2019 were retrospectively analyzed. According to different pancreaticojejunostomy methods，the patients were divided into the traditional group（n=35）and the modified group（n=45），Traditional group：continuous pancreaticointestinal anastomosis through row；Modified group：underwent modified continuous pancreaticointestinal anastomosis. SPSS 22.0 statistical software was used for analysis. Perioperative indexes and postoperative quality of life were expressed as（

There was no significant difference in operation time and intraoperative blood loss between the two groups（P>0.05）. The pancreaticoenterostomy time of the modified group was significantly longer than that of the traditional group（P<0.05），and the duration of drainage tube indplacement and postoperative hospital stay were significantly shorter than that of the traditional group（P<0.05）. here was no significant difference in the incidence of postoperative biochemical fistula，abdominal infection，postoperative bleeding，biliary fistula and gastroparalysis between the two groups（P>0.05），and there was no grade C pancreatic fistula in the two groups，while the incidence of grade B pancreatic fistula in the modified group was significantly lower than that in the traditional group（2.2% vs. 20.0%，P<0.05）；There was no significant difference in the physiological function，physiological function，physical pain，general health，social function and emotional function between two groups at 3 months after operation（P>0.05）.

The modified through penetrating-suture pancreaticojejunostomy after “G” shaped path resection is safe and effective in PD，which can accelerate postoperative recovery，shorten the hospitalization time，reduce the occurrence of B-grade pancreatic fistula，which is worthy of clinical application.