To explore the effect of immediate breast reconstruction after modified radical mastectomy on the clinical prognosis and quality of life of breast cancer patients.

Data of 71 young breast cancer patients from January 2016 to March 2018 were retrospectively analyzed，according to different surgical methods，they were divided into observation group（n = 36）and（n = 35）control group. The control group was treated with modified radical mastectomy with sparing nipple and areola，and the observation group was treated with immediate breast reconstruction after modified radical mastectomy with sparing nipple and areola. All patients were followed up. The SPSS 19.0 statistical software was used for analysis，Surgical indicators，FACT-B score and other measurement data were represented by（

The operation time and intraoperative blood loss in observation group were longer than those in control group（P<0.05）. There was no significant difference in the number of dissected lymph nodes between the two groups（P>0.05）. One year after surgery，FACT-B scores was increased in both groups，and the observation group FACT-B scores was higher than control group（P<0.05）. The observation group local recurrence rate was 8.3%，the distant metastasis rate was 6.7%，and 10.0% and 10.0% in the control group. There was no significant difference in local recurrence rate and distant metastasis rate between 2 groups（P>0.05）.

Immediate breast reconstruction after modified radical mastectomy with sparing nipple and areola can maintain the original shape of breast，effectively improve the quality of life of patients after operation，without increasing the risk of local recurrence and distant metastasis in the short term.