Abstract:
Objective To investigate the short-term clinical efficacy and immune level of laparoscopic radical gastrectomy for early gastric cancer.
Methods The data of 124 patients with early gastric cancer from January 2016 to December 2018 were retrospectively analyzed, and they were divided into laparoscopic surgery group and open surgery group, with 62 patients in each group.SPSS21.0 statistical software was used to analyze the data. Perioperative indicators and immunological indicators were represented by(±s), and independent t-test was performed. The clinical treatment effect was analyzed by rank sum test, the complication rate was tested by χ2 test, and P<0.05 was considered statistically significant.
Results The intraoperative blood loss of patients in the endoscopic group was less than that in the open group, while the operative time, anal exhaust time, out-of-bed activity time, feeding time and postoperative hospital stay were shorter than those in the control group (P<0.05). The incidence of total adverse reactions (9.7%) was lower than that in the open group (25.8%). After treatment, the hs-CRP, IL-6 and TNF-α values of the two groups were increased, while those of the endoscopic group were lower than those of the open group, with statistically significant differences (P<0.05).
Conclusion Laparoscopic radical gastrectomy is superior to open radical gastrectomy in the treatment of patients with early gastric cancer, with fewer postoperative complications and less impact on immune function, so it is suitable for clinical application.
Key words:
Stomach neoplasms,
Laparoscopes,
Gastrectomy,
Survival analysis
Wei Zhang, Zhenhua Cai, Ruiqing Zhou, Xiaohui Liu, Qilin Jiang, Hongbo Liu, Yongjie Dong, Yunzhang Feng. The study on the short-term clinical efficacy and stress factors of laparoscopic radical gastrectomy for early gastric cancer[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(04): 411-413.