To investigate the effect and postoperative liver function of laparoscopic hepatectomy with low central venous pressure in patients with primary liver cancer.

Data of 78 patients with primary liver cancer treated in our hospital from January 2014 to December 2018 were retrospectively analyzed. According to different surgical methods, the patients were divided into laparoscopic hepatectomy group (43 cases) and conventional laparotomy group (35 cases). Statistical software SPSS24.0 was used for data analysis. Preoperative and postoperative indicators of liver function at 1 d and 7 d were described by (±s). Independent t test was used for inter-group comparison, and paired t test was used for intra-group comparison, complications such as counting data were compared with χ² test , P<0.05 indicated statistically significant difference.

Compared with the laparotomy group, the intraoperative liver resection time was shorter, the amount of blood loss was less, the postoperative exhaust time was shorter, and the hospital stay was shorter, with statistically significant differences (P<0.05). The incidence of postoperative complications (bile leakage , pulmonary infection, wound infection)was lower in the laparoscopic group than in the laparotomy group (P>0.05). Comparison of postoperative liver function indicators showed that ALT, AST and TBIL levels in the laparoscopic group were better than those in the laparotomy group (P<0.05).

Laparoscopic hepatectomy with low central venous pressure is more effective in the treatment of primary hepatocellular carcinoma with lower incidence of complications and faster recovery of liver function.