To explore the predictive value of perioperative NRS score and Galon immune score for postoperative prognosis of patients with colorectal cancer.

Retrospective analysis were performed in 97 patients with colorectal cancer who underwent radical resection from October 2014 to October 2016. Statistical analysis were performed by using SPSS 21.0 software. Kplan-Meier method and Cox regression model were used to analyze the correlation between perioperative NRS score, primary lesion Galon immune score, postoperative prognosis of patients and clinicopathological features. ROC curves were used to test the predictive value of the combined score prediction model for total postoperative survival of patients with colorectal cancer, and Kplan-Meier was used to analyze the prognosis, A P value <0.05 was considered as statistically significant difference.

The 1-year, 2-year and 3-year cumulative survival rates of 97 enrolled patients were 95.9%, 89.7% and 70.1%, respectively. Compared with perioperative NRS score 1 and 2, Patients with NRS score 0 had a better 3-year overall survival rate (log-rank χ²=19.337, P=0.000). In terms of primary lesion Galon immune score, patients score 0/1/2/3/4 appeared to have a gradually poor 3-year overall survival rate (log-rank χ²=30.511, P=0.000). The value of perioperative NRS score combined with Galon immune score in predicting postoperative prognosis of patients with colorectal cancer was higher than that of a single score, with an AUC value of 0.785, a sensitivity of 65.93%, a specificity of 84.12%, and a yoden index of 0.501. The 3-year overall survival rate of the low-risk group was better than that of the high-risk group (log-rank χ²=12.517, P=0.000).

Perioperative nutrition score combined with tumor immune score has a high predictive value for prognosis of patients with colorectal cancer, which could be applied in clinical practice.