Clinical Analysis of laparoscopic sleeve gastrectomy in treating patients with type 2 diabetes and high BMI

doi:10.3877/cma.j.issn.1674-3946.2020.02.009

Abstract

Abstract:

Objective

To investigate the feasibility and efficacy of laparoscopic sleeve gastrectomy (LSG) in the treatment of patients with type 2 diabetes (T2DM) and high body mass index (BMI).

Methods

The clinical data of 24 patients with T2DM and high BMI who underwent LSG were analyzed retrospectively from 2010 to 2016. Statistical analysis were performed by using SPSS 17.0 software package. Measurement data such as preoperative/postoperative body weight and HbAlc levels were expressed as (±s) and examined by using independent t-test. Count data were expressed as frequency and percentage, and were compared by using χ² test. A P value of <0.05 was considered as statistically significant difference.

Results

The average baseline weight of 24 patients was (117.2±30.2) kg, which decreased significantly to (100.3±22.1) kg, (91.6±22.4) kg, (81.3 ± 16.5) kg and (80.3 ± 14.3) kg at 3 months, 6 months, 12 months and 24 months after surgery respectively (P<0.001). The preoperative average baseline HbA1c was (8.5±2.2)%, which was significantly decreased to (6.4±1.6)%, (5.8±1.1)%, (5.7± 0.7)% and (5.3±0.6)% at 3 months, 6 months, 12 months, and 24 months, respectively (P<0.001). 19 patients with type 2 diabetes who underwent sleeve gastrectomy discontinued insulin and oral hypoglycemic agents. According to the level of blood glucose control, remission rate of 24 patients was 79.2% 24 months after surgery. Except one case, other 17 patients with hypertensive stopped antihypertensive treatment after surgery.

Conclusion

LSG is a safe, feasible and effective for the treatment of patients with T2DM and high BMI. It is worthy of widespread clinical application.

Key words: Diabetes mellitus, Sleeve gastrectomy, Laparoscopes, Gastrectomy, High body mass index

Xinqiang Zhu, Hailong Huang, Xuetong Jiang, Xitai Sun. Clinical Analysis of laparoscopic sleeve gastrectomy in treating patients with type 2 diabetes and high BMI[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(02): 132-135.

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References 19

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观察指标	术前	术后
观察指标	术前	3个月	6个月	12个月	24个月
体重(kg)	117.2±30.2	100.3±22.1^a	91.6±22.4^a	81.3±16.5^a	80.3±14.3^a
HbA1C(%)	8.5±2.2	6.4±1.6^a (<0.001)	5.8±1.1^a (<0.001)	5.7±0.7^a (<0.001)	5.3±0.6^a (<0.001)
多余体重减轻比(%)		32.5±26.6^a	49.4±29.2^a	67.1±30.4^a	70.1±19.3^a
BMI(kg/m²)	45.5±12.1	37.3±7.6^a	33.5±7.0^a	30.3±6.1^a	30.5±5.3^a

观察指标	术前	术后
观察指标	术前	3个月	6个月	12个月	24个月
体重(kg)	117.2±30.2	100.3±22.1^a	91.6±22.4^a	81.3±16.5^a	80.3±14.3^a
HbA1C(%)	8.5±2.2	6.4±1.6^a (<0.001)	5.8±1.1^a (<0.001)	5.7±0.7^a (<0.001)	5.3±0.6^a (<0.001)
多余体重减轻比(%)		32.5±26.6^a	49.4±29.2^a	67.1±30.4^a	70.1±19.3^a
BMI(kg/m²)	45.5±12.1	37.3±7.6^a	33.5±7.0^a	30.3±6.1^a	30.5±5.3^a

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