To investigate the effect of jejunal interposition anastomosis in digestive tract reconstruction after total gastrectomy for proximal gastric cancer and its effect on digestive function of patients.

80 patients with proximal gastric cancer who underwent radical total gastrectomy in our hospital from April 2016 to August 2018 were selected. 40 patients who underwent gastrointestinal reconstruction by jejunal interposition anastomosis were included in the observation group, and 40 patients who underwent gastrointestinal reconstruction by esophago-jejunal Roux-en-Y were included in the control group. All the data were analyzed by SPSS 16.0. The operation-related data and gastrointestinal hormone levels were described by (±s), the independent sample t test was used for comparison between the two groups, and the paired t test was used for comparison at different time. The counting data were compared by χ² test; P<0.05 had statistical significance.

There was no significant difference in operation time, intraoperative bleeding volume, number of lymph nodes dissected and length of hospital stay between the two groups (P>0.05). Three months after operation, the levels of serum gastrin (GAS), motilin (MTL) and somatostatin (SS) in the two groups were significantly lower than those before operation, and the decrease in the control group was more significant, the level of cholecystokinin (CCK) was significantly higher than that before operation, the differences were statistically significant (P<0.05). The complication rate of the observation group was 10.00%, which was lower than that of the control group of 27.50% (χ²=4.021, P=0.045).

Jejunal interposition anastomosis has less influence on digestive function and lower incidence of complications after radical total gastrectomy for proximal gastric cancer.