Abstract:
Objective To explore the clinical efficacy of laparoscopic appendectomy in patients with acute appendicitis and its influence on the level of inflammatory factors.
Methods The data of 160 patients with acute appendicitis from April 2019 to April 2022 were retrospectively analyzed and divided into two groups according to different operation methods：endoscopic group and laparotomy group，80 cases each. Statistical software SPSS 21.0 was used to process the data. The incidence of complications was represented by［n（%）］，and χ2 test was used for comparison between groups. Perioperative indicators，inflammatory factors and quality of life scores were expressed as（
±
s），and independent
t test was used for comparison between groups.
P<0.05 was considered to be statistically significant.
Results The operative time，intraoperative blood loss，anal exhaust time，hospital stay，quality of life score and incidence of complications in the endoscopic group were significantly better than those in the open group，with statistical significance（P<0.05）. The levels of C-reactive protein（CRP）and procalcitonin（PCT）in the endoscopic group were significantly lower than those in the open group 3 days after surgery，with statistical significance（P<0.05）. The hospitalization cost in endoscopy group was significantly higher than that in laparotomy group（P<0.05）.
Conclusions Compared with open surgery，laparoscopic appendectomy for patients with acute appendicitis has less trauma，higher safety，and is conducive to postoperative repair，but the cost is higher，and can be selected clinically according to the actual situation of patients.
Key words:
Acute Appendicitis,
Laparoscopes,
Appendectomy,
Treatment Outcome,
C-Reactive Protein,
Procalcitonin
Shusen Feng, Dongcheng Zhang, Qi Guo, Haolu Zhang, Kuo Chen. Clinical effect of laparoscopic appendectomy on acute appendicitis and its influence on inflammatory factors[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(04): 447-450.