The clinical efficacy and changes of gastric pressure after laparoscopic proximal gastrectomy（LPG）for gastrointestinal reconstruction were compared and analyzed.

Seventy gastric cancer patients receiving LPG from January 1，2018 to December 2021 were selected as the research objects. The patients were divided into two groups by random number table method，35 cases in the combined group and 35 cases in the double-channel group. Patients in both groups were treated with LPG. The combined group was treated with esophagojejunal anastomosis after self-traction（SPLT）and dual anti-reflux dual-channel residual gastrojejunal anastomosis（DADT）for digestive tract reconstruction，and the double-channel group was treated with double-channel anastomosis for digestive tract reconstruction. The data were processed by SPSS 22.0 software，and measurement data such as perioperative indicators were represented by（

There were no significant differences in operation time，digestive tract reconstruction time，intraoperative blood loss，postoperative anal exhaust time and postoperative hospital stay between 2 groups（P>0.05）. The number of lymph node dissection in the combined group was significantly higher than that in the two-channel group，and the total incidence of postoperative complications was significantly lower than that in the two-channel group（11.4%vs.31.4%），with statistical significance（P<0.05）. There was no interaction between time and method on gastric pressure and PH level（P>0.05），but the main effect of time and method on gastric pressure and PH level was significant（P<0.05）.

Compared with the dual-channel digestive tract reconstruction scheme，SPLT+DADT in LPG not only improves the lymph node clearance rate，but also effectively reduces the occurrence of postoperative complications and further improves the safety of surgery. Moreover，studies have found that changes in gastric pressure are closely related to the occurrence of gastroesophageal reflux.