To investigate the safety and efficacy of double tracer（indocyanine green combined with carbon nanoparticles）navigation in laparoscopic radical gastrectomy for gastric cancer.

Prospective clinical study to carry out the single arm and opening up，from July 2021 to September 2021 were included in a total of 15 patients with na line standard，into the group of patients at the same time accept indocyanine green with nano carbon tracer，including indocyanine green injection by "six point method" laparoscopic serosal surface，nano carbon injection by "sandwich method"，the mucosa under gastroscope surface Standardized D2 laparoscopic radical gastrectomy and lymph node sampling were performed. There were 11 males（73.3%）and 4 females（26.7%），with an average age of（57.1±12.8）years. There were 6 cases（40.0%）of laparoscopic radical total gastrectomy（π anastomosis）and 9 cases（60.0%）of laparoscopic radical distal subtotal gastrectomy（BiⅡ+Braun anastomosis）. The operation time，intraoperative blood loss，postoperative hospital stay，complications，second operation rate，survival rate，postoperative pathological stage，the number of lymph nodes detected at each station and the total number were analyzed.

The mean operation time was（254.7±40.1）min，intraoperative blood loss was（90.0±51.7）ml，and postoperative hospital stay was（10.5±1.5）days. There were no serious complications or unplanned reoperation. The total number of lymph nodes dissected was（44.6±13.1）.

Dual tracer navigation（indocyanine green combined with carbon nanoparticles）is safe and effective in laparoscopic radical gastrectomy.