To investigate the effects of accelerated rehabilitation surgery（FTS）on gastrointestinal function，inflammatory factors and nutritional index in patients with hilar cholangiocarcinoma（HCCA）.

A total of 82 HCCA patients who underwent laparoscopic radical surgery from January 2019 to January 2021 were divided into FTS group and control group of 41 according to the random number table method with 41 patients in each group. Patients in the control group received conventional rehabilitation surgery，and patients in the FTS group received fast track surgery. SPSS 25.0 was used to process the data，gastrointestinal function，preoperative and postoperative 3 d inflammatory response and nutritional index changes were expressed by（

Anal exhaust time，first defecation time and ambulation time in FTS group were shorter than those in control group（P<0.05）. The incidence of complications in FTS group（9.8%）was lower than that in control group（29.3%）（P<0.05）. The levels of serum tumor necrosis factor α（TNF-α），C-reactive protein（CRP）and interleukin-6（IL-6）in 3 days after surgery in 2 groups were higher than those before surgery（P<0.05），but the levels of above three indexes in FTS group were lower than those in control group（P<0.05）. The levels of serum transferrin（TRF），albumin（ALB）and prealbumin（PAB）in 3 days after surgery in 2 groups were lower than those before surgery（P<0.05），but the levels of above three indexes in FTS group were higher than those in control group（P<0.05）.

FTS can promote the recovery of gastrointestinal function，reduce inflammatory reaction and improve the nutritional status of HCCA patients after laparoscopic surgery.