To investigate the perioperative value of of enhanced recovery after surgery（ERAS）in D2 radical gastrectomy for advanced gastric cancer.

A retrospective analysis was performed on the clinical data of 637 patients with gastric cancer from May 2018 to May 2020. According to different methods of perioperative management，they were divided into ERAS group（n=327 cases）and traditional group（n=310 cases）. SPSS 22.0 was used for statistical analysis. The intraoperative and postoperative related indexes and stress indexes were tested by（

In ERAS group，postoperative fluid infusion，length of hospital stay，time of first ventilation，time of first feeding，time of gastric tube indwelling and time of drainage tube removal were all shorter than those in traditional group（P<0.05）. The levels of C-reactive protein and white blood cells in the ERAS group were lower than those in the traditional group 1 and 3 days after operation，and the differences were statistically significant（P<0.05）. The total incidence of postoperative complications and 1 year recurrence rate in ERAS group were lower than those in traditional group（30.6% VS. 48.4%，6.4% VS. 20.9%），with statistical significance（P<0.05）.

The application of ERAS in D2 radical gastrectomy for advanced gastric cancer can reduce the time of initial postoperative defecation，drainage tube removal，feeding，etc.，which can help reduce the inflammatory response of the body and reduce the incidence of postoperative complications.