To study the clinical effect of open pancreatic necrosis debridement and laparoscopic-assisted pancreatic necrosis clearance in the treatment of infective pancreatic necrosis due to acute pancreatitis.

The clinical data of 100 patients with acute pancreatitis complicated with infectious pancreatic necrosis from February 2018 to March 2020 were retrospectively analyzed. According to different treatment methods, the patients were divided into OP group (n=59cases) and LA group (n=41cases). SPSS24.0 used for analysis. Perioperative indexes, blood inflammatory indexes were expressed by (±s), and Independent t test was used. Postoperative complications were counted by χ² test. P<0.05 was considered statistically significant.

The operation time of the LA group was longer than that of OP group, but the amount of intraoperative blood loss, the time of open diet, postoperative hospital stay were less than those of the OP group, with the statistical significant (P<0.05). The total incidence of postoperative complications was 22.0% in OP group and 12.2% in LA group, with no statistically significant (P>0.05). One week after surgery, blood WBC, neutrophil, CRP and PCT in the two groups were significantly lower than those before surgery (P<0.05).

Laparoscopic-assisted pancreatic necrosis clearance is safe and effective, with obvious debridement effect, and has the advantages of less trauma and faster postoperative recovery.