To compare the clinical outcome between the laparoscopic gastric-function-preserving surgery and radical resection for early gastric cancer.

The data of 82 patients with early gastric cancer underwent the gastric resection from July 2015 to December 2019 were analyzed retrospectively. According to different surgical procedures, they were divided into the retention group who received the laparoscopic gastric function preservation (n=42 cases), and the radical group who underwent laparoscopic radical resection (n=40 cases). Statistical analysis were performed by using SPSS23.0 software. The data of normally distributed operation-related indexes, quality of life and nutritional status were expressed as (±s), and the difference between the two groups were examined by using t test. Complications expressed as the rate were examined by using χ² test . A P value of <0.05 was considered as statistically significant difference.

Compared with the radical group, much less harvested lymph nodes and intraoperative bleeding , increased operational time and shorter time of anal exhaust and hospitalization were observed respectively in the retention group (P<0.05). The scores of GLQI and MNA in the retention group were higher than those in the radical group on 6 months after surgery (P<0.05). There was no significant difference between two groups in terms of the incidence of postoperative complications (14.3% vs. 17.5%, P>0.05).

In the treatment of early gastric cancer, laparoscopic gastric-function-preserving surgery could improve the nutritional status and the quality of life of patients compared with laparoscopic radical gastrectomy, however without obvious advantage in reducing postoperative complications.