To study the clinical effect of bariatric and metabolic surgery on obese patients with type 2 diabetes mellitus(T2DM) and analyze the influencing factors.

The clinical data of 85 obese patients with T2DM who underwent metabolic weight loss surgery from January 2016 to December 2018 were retrospectively analyzed. Statistical software SPSS 24.0 was used for data analysis. The measurement data of various indicators before and after surgery were expressed as (±s), and independent sample t test was performed; The gender and operation type were tested by χ² test. The influencing factors of clinical efficacy were analyzed by Logistics regression. P<0.05 was considered statistically significant.

The clinical indicators of all patients were significantly improved after 1 year follow-up (P<0.05). 63 patients reached the standard of T2DM remission, (74.1%). There was no significant difference in gender, age, weight-loss surgery, 2HPG, TCHO and TG between the remission group and the non remission group (P>0.05), but there was significant difference in BMI, T2DM course, FBG, HbAlc and fasting C-peptide (P<0.05). Further logistic regression analysis showed that BMI ≥32 kg/m², duration of T2DM≥4 years and fasting C-peptide<3ng/ml were independent risk factors for the efficacy of bariatric metabolic surgery (P<0.05).

The bariatric and metabolic surgery is an effective treatment for obesity patients with T2DM, especially for the patients with BMI 32 kg/m², T2DM course 4years and fasting C peptide 3ng/ml before operation were more effective.