To explore the learning curve of laparoscopic partial hepatectomy (LH) in single-center.

The general data of 118 cases of LH from June 2014 to June 2020 were analyzed by using learning curve analysis. SPSS 22.0 were used for statistical analysis. Minitab 17.0 was used to draw CUSUM control chart and fitting curve. When P≤0.05, the fitting curve was recognized as successful, and the R2 value was used to judge the goodness of fitting. The closer the R² value is to 1, the better the goodness of fitting is.

The cumulative operative time and the fitting curve formula: CUSUM(n)=27.86+ 17.00 n-0.1938 n²+ 0.000415 n²(n is the number of cases), the fitting coefficient R²=0.963. According to the fitting curve analysis, the learning curve of laparoscopic partial hepatectomy was divided into three phases: the early phase group (1~36 cases), the middle phase group (37~88 cases) and the late phase group (89~118 cases). The operative time (P<0.001), intraoperative blood loss (P=0.003) and postoperative time of hospitalization (P<0.001) in the late phase group were better than those in the other two phase groups, with statistical significant difference. There were no significant difference in conversion rate (P=0.336) and the incidence of postoperative complications (P=0.099) among the three groups.

Cumulation and analysis show that the learning curve of laparoscopic partial hepatectomy consists of three characteristic phases. The operator basically mastered LH need to complete a cumulative total of 37~88 cases.