To investigate the safety of proximal gastrectomy by using two types digestive tract reconstruction and to compare the quality of life of patients after surgery.

From September 2016 to January 2019, clinical data of 57 patients with early staging gastric cancer, who underwent proximal gastrectomy plus interposition jejunostomy, were analyzed retrospectively. According to different type of reconstruction, patients were divided into the single-channel group (n=26, single-channel interposition jejunum anastomosis) and into the double-channel group (n=31, double-channel interposition jejunum anastomosis). Statistical analysis were performed by using SPSS20.0 software. Measurement data such as perioperative indicators, nutritional indicators and quality of life scores were represented as (±s) and were examined by using independent t test. Postoperative complications were analyzed by using χ² test. Kaplan-meier method was used for survival analysis. The rank sum test were used for the reflux esophagitis grade and TNM stage. A P value of <0.05 was considered as statistical significant difference.

There were no significant differences between two groups in terms of operation time, blood loss, ventilation time, hospital stay, total incidence of postoperative complications and total incidence of reflux esophagitis (P>0.05). The body weight of patients in the single channel group was significantly higher than those in the double channel group one month after surgery (P<0.05). The nutritional indexes in the single channel group were better than those in the double channel group (P<0.05). There was no significant difference in terms of functional status score and overall health status score at each postoperative time point between two groups (P>0.05).

It is safe and feasible to perform single or double channel interposition Jejunostomy after resection of proximal gastric cancer, however the recovery status of patients after single channel anastomosis is better than that after double channel anastomosis.