To evaluate the effect of radical operation for pancreatic cancer combined with vascular resection and reconstruction on the incidence of complications and quality of life in patients with pancreatic cancer.

The clinical data of 145 pancreatic cancer patients with radical operation for pancreatic cancer from May 2015 to May 2018 were retrospectively analyzed. According to the intraoperative vascular resection and reconstruction or not, all patients were divided into Group A (no vascular resection, n=77), Group B (venous resection, n=58), and Group C (arterectomy, n=10). SPSS 24.0 software was used for data processing. Surgical related indicators and quality of life scores were expressed as (±s). Comparisons between groups were tested by t test, and comparisons between multiple groups were analyzed by single factor analysis of variance. P<0.05 was considered statistically significant.

The operation time, intraoperative bleeding volume, blood transfusion volume and the incidence of complications in Group C was higher than those in Group B and Group C (P<0.05); After surgery for 6 months, the scores of short form-36 health status questionnaire (SF-36) and Karnofsly’s performance status (KPS) in the three groups were higher than those before surgery (P<0.05), but there was no statistical difference among the three groups (P>0.05); There was no dead cases in the three groups during surgery, the median survival time of Group A, Group B and Group C were (16.2±1.5) months, (15.3±1.2) months, (14.2±1.9) months, and the difference was not statistically significant (P>0.05).

For patients with pancreatic cancer that invades the superior mesenteric artery, superior mesenteric vein, and portal vein, if meet the surgical indications, it can be combined with revascularization during the operation. Although it will increase the amount of bleeding and complications, it can achieve the similar prognosis compared with the patients without vascular invasion.