To evaluate the influence of radical operation for pancreatic cancer combined with vascular resection and reconstruction on the incidence of complications and quality of life in patients with pancreatic cancer.

The clinical data of 145 pancreatic cancer patients with radical operation for pancreatic cancer from May 2015 to May 2018 were retrospectively analyzed. According to the intraoperative vascular resection and reconstruction, all patients were divided into A group (non-vascular resection, n=77), V group (venous resection and reconstruction, n=58) and O group (arterial resection and reconstruction, n=10). SPSS 24.0 software was used for data processing. The surgical indexes, quality of life and survival time were expressed as (±s). The t test was adopted between groups, the one-way analysis of variance was adopted among groups; The χ² test was adopted to compare the complications among groups. α=0.05, P<0.05 were considered statistically significant.

The operation time, intraoperative bleeding volume, blood transfusion volume and the incidence of complications in O group were higher than those in V group and A group (P<0.05); After surgery for 6 months, the scores of short form-36 health status questionnaire (SF-36) in the three groups were higher than those before surgery (P<0.05), but there was no statistical difference among the three groups (P>0.05); There was no dead cases in the three groups during surgery, the median survival time of A group, V and O group were (16.2±1.5) months, (15.3±1.2) months, (14.2±1.9) months, and the difference was not statistically significant (P>0.05).

Radical operation for pancreatic cancer combined with arterial and venous resection has shortcomings such as long operation time, high bleeding volume and high incidence of complications, but it can obtain similar survival time, prognosis and quality of life with non-vascular resection and reconstruction. Therefore, vascular resection and reconstruction can be recommended in accordance with the indications for surgery.