To investigate the efficacy and prognosis of laparoscopic thyroidectomy by using combined transthoracic breast and transoral approach for early/middle staging thyroid cancer.

Retrospective analysis were performed in 64 patients with early/middle staging thyroid cancer from March 2015 to April 2018, who were divided into group A (transthoracic breast approach, 28 cases) and group B (combined transthoracic breast and transoral approach, 36 cases). Data analysis was performed by using SPSS21.0 software. Measurement data such as perioperative indicators were expressed as ±s, and were examined by using independent t test. Count data such as complication rate were examined by chi square test. A P value <0.05 was considered as statistically significant difference.

The operation time, drainage time and number of harvested lymph nodes in group A were lower than those in group B respectively (all P<0.05). There were no significant difference in terms of intraoperative blood loss and hospitalization time between the two groups (P>0.05). The satisfaction score of patients in group B was higher than that in group A (P<0.05). There were no serious complications such as permanent parathyroid function injury in both groups. There was no significant difference in the incidence of complications between the two groups (P>0.05).

Laparoscopic thyroidectomy by using combined transthoracic breast and transoral approach for early/middle staging thyroid cancer could achieve complete clearance of the central lymph nodes and better clinical outcome, without increase of postoperative complications, however with longer operation time.