To observe the clinical value of modified radical with nipple-sparing mastectomy combined with immediate prosthesis implantation for early stage breast cancer.

The clinical data of 93 patients with early stage breast cancer treated in our hospital were retrospectively analyzed and divided into prosthesis implantation group (treated with modified radical mastectomy and immediate prosthesis implantation, n=48) and traditional surgery group (treated with traditional modified radical mastectomy, n=45) according to the different surgical procedures. The data was analyzed using the statistical software SPSS19.0. The age, tumor diameter, body mass index of the two groups were adopted by (±s) and compared by the independent sample t test; The TNM stage, the excellent and good rate of breast appearance, postoperative mental status and quality of life, total incidence of complications of the two groups were compared by χ² test, P<0.05 was considered statistically significant.

The total complication rate in the prosthesis implantation group and the traditional surgery group were 25.0% and 20.0% (P>0.05). The excellent and good rate of breast appearance in the prosthesis implantation group was 93.8% at 3 months postoperatively, which was significantly higher than 77.8% in the traditional surgery group (P<0.05). The incidence of anxiety, depression, fear, interpersonal sensitivity and self-image disorder in the prosthesis implantation group were 25%, 16.7%, 31.3%, 20.8%, 14.6% at 6 months after operation, which were significantly lower than 46.67% and 46.7%, 35.6%, 53.3%, 40%, 33.3% in the traditional surgery group (P<0.05). There were no significant difference in the 2-year disease-free survival rate, the recurrence rate and distant metastasis rate, mortality rate during follow-up between the two groups (P>0.05).

The modified radical with nipple-sparing mastectomy combined with immediate prosthesis implantation in the treatment of early breast cancer can meet the needs of patients with breast reconstruction, which does not affect the curative effect and can improve the aesthetic of breast appearance, improve the patient’s postoperative psychological and quality of life, is worthy of promoting.