To explore the effect of increasing intra-abdominal pressure on patient’s prognosis during laparoscopic radical surgery for colorectal cancer.

A retrospective analysis of clinical data of 114 cases of colorectal cancer patients undergoing laparoscopic radical resection in our hospital from January 2014 to June 2017 was made. According to the different intra-abdominal pressure, patients were divided into 3 groups: Group A: 10 mmHg (1 mmHg=0.133 kPa), 36 cases; group B: 12 mmHg, 41 cases; group C: 15 mmHg, 37 cases. All data were analyzed by SPSS 20.0 statistical software. The postoperative recovery conditions and the peripheral blood D-lactic acid, IL-6 and TNF-α level were presented as (±s) and examined by t test. The proportion of pulling out nasogastric tube within 6 h after operation and the incidence of postoperative complications were compared among three groups by chi square.

There was no statistical difference in the proportion of pulling out nasogastric tube within 6 h after operation, first exhaust time, first defecation time, first bowel sounds time, first meal time and hospitalization time in the three groups (P>0.05). There was no statistically significant difference in the incidence of postoperative complications in the three groups (P>0.05). Compared with preoperative, the postoperative D-lactic acid and IL-6 level were signi? cantly increased (P<0.05), but the postoperative TNF-α level has no significant change (P>0.05). The postoperative D-lactic acid level in group C were significantly higher than group A and B (P<0.05).

The increasing intra-abdominal pressure during laparoscopic radical surgery for colorectal cancer has no significant effect on patient’s prognosis.