研究三维重建技术对肝门部胆管癌(HCCA)术前解剖学分型的准确性，及三维重建联合吲哚菁绿(ICG)分子荧光成像技术的临床应用价值。

选取2017年3月至2020年3月行手术治疗的86例HCCA患者为研究对象，随机分为联合组和常规组各43例。联合组在三维重建模型下+ICG分子荧光成像技术指导手术方案，常规组采用传统影像学指导手术方案。采用SPSS20.0软件对数据进行处理，围术期指标等计量资料以(±s)表示，采用独立样本t检验；术后并发症等计数资料采用χ²检验；生存分析采用K-M法；P<0.05为差异有统计学意义。

联合组肿瘤分型诊断的准确性显著高于常规组(100% vs. 72.1%)，P<0.05；联合组侦测预切除肝脏区域方案与实际手术方式比较一致率显著高于常规组(95.3% vs. 79.1%)，P<0.05；两组患者均未发生围术期死亡，联合组手术时间、肝门Pringle阻断时间及术中出血量优于常规组(P<0.05)；联合组术后并发症总发生率明显低于常规组(13.9% vs. 37.2%)，差异均有统计学意义(P<0.05)。术后进行3～51个月随访，K-M曲线分析显示两组术后无病生存及累积总生存率差异无统计学意义(P>0.05)。

三维重建联合ICG分子荧光成像技术可对HCCA进行术前准确评估，且可缩短手术时间，减少术中出血，降低术后并发症发生率，可在临床推广应用。

To investigate the accuracy of 3D reconstruction technique in preoperative anatomical classification of hilar cholangiocarcinoma (HCCA), and to explore the clinical application value of three-dimensional reconstruction combined with ICG imaging.

A total of 86 HCCA patients underwent surgical treatment from March 2017 to March 2020 were selected as the study subjects and were randomly divided into the combined group(43 cases) and the conventional group(43 cases), .The combined group was guided with the ICG imaging under the three-dimensional reconstruction model, while the conventional group was guided with the conventional imaging technique. Spss20.0 software were used to process the data. The perioperative indicators and other measurement data were expressed as (±s), and the comparison were analyzed by using independent t test; the postoperative complications and other count data were analyzed by using χ² test; K-M method were used for survival analysis; A P value of <0.05 was considered as statistically significant difference.

The accuracy of tumor typing diagnosis in the combined group was significantly higher than that in the conventional group (100% vs. 72.1%) P<0.05; The consistency rate of the combined group’s detection of pre-resection of the liver area compare with the actual surgical method was significantly higher than that in the conventional group (95.3% vs. 79.1%) P<0.05; There was no perioperative death both in the two groups. The operative time, hepatic Pringle block time and intraoperative bleeding in the combined group were better than those in the conventional group (P<0.05); The total incidence of postoperative complications in the combined group was significantly lower than that in the conventional group (13.9% vs. 37.2%) with significant differences (P<0.05). Follow-up of 3 to 51 months after operation, K-M curve analysis showed that there was no significant difference in terms of disease-free survival and cumulative overall survival rate between the two groups (P>0.05).

Three-dimensional reconstruction combined with ICG imaging could accurately evaluate HCCA before surgery, shorten the operative time, reduce intraoperative bleeding and could reduce the incidence of postoperative complications, which could be widely applied in clinical practice.