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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (02): 166-169. doi: 10.3877/cma.j.issn.1674-3946.2025.02.014.

• Original Articles • Previous Articles    

An open-arm prospective study of intravenous indocyanine green guided radical gastrectomy for gastric cancer

Shichao Ai1, Yiwen Sun1, Peng Song1, Xiaofei Shen1, song Liu1, Feng Sun1, Xiaofeng Lu1,(), Meng Wang1,(), Wenxian Guan1,()   

  1. 1.Division of Gastric Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Medical School, Nanjing University, Nanjing Jiangsu Province 210008,China
  • Received:2023-11-21 Online:2025-04-26 Published:2025-02-25
  • Contact: Xiaofeng Lu, Meng Wang, Wenxian Guan

Abstract:

Objective

To investigate the safety and efficacy of intravenous indocyanine green navigation surgery in radical gastrectomy.

Methods

Nine patients receiving intravenous indocyanine green guided radical gastrectomy were enrolled.All patients underwent standard D2 lymph node dissection and lymph node sorting.Indocyanine green was injected at 0.5h, 4h and 12h before surgery, respectively.Perioperative indexes, imaging effects of tumor and lymph nodes, the ratio of tumor and lymph nodes to surrounding tissue,the number of lymph nodes sorted at each station and the total number were analyzed.Measurement data with normal distribution were represent as (Mean±SD).

Results

The mean operation time of the included patients was (206.7±33.1) min, the intraoperative blood loss was (161.1±48.6) ml, and the postoperative hospital stay was (10.1±1.8) d.None of the 9 patients had serious complications.The imaging of tumor and lymph nodes could be achieved at all three time points.The highest ratio of tumor to normal gastric mucosal tissue was (2.5±0.4) at 0.5h,and the highest ratio of lymph node to surrounding tissue was (1.9±0.6) at 12h.The total number of lymph nodes was (74.0±29.2).

Conclusions

Intravenous indocyanine green navigation radical gastrectomy is effective.

Key words: Stomach Neoplasm, Radical Gastrectomy, Indocyanine Green, Tumor Localization, Lymph Node Mapping

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