To investigate the effect of indocyanine green (ICG) fluorescence imaging guided laparoscopic cholecystectomy (LC) on patients with gallstones and cholecystitis.

83 patients with gallstones and cholecystitis who underwent LC from January 2021 to January 2023 were prospectively included as study subjects. They were divided into ICG group (n=42 cases) and conventional group (n=41 cases) by random number table method. The conventional group was treated with LC, and the ICG group was treated with LC guided by ICG fluorescence imaging. Data were analyzed by SPSS27.0, measurement data such as perioperative indicators were described by (), and independent sample t test was used. The statistical data of postoperative complications were expressed with [cases (%)] and Chi-square test was performed. P<0.05 was considered statistically significant.

The first detection of common bile duct, hepatic duct and gallbladder duct in ICG group was higher than that in conventional group [(69.1% vs. 26.8%, 59.5% vs. 31.7%), P<0.05]. After complete dissection, the common bile duct and hepatic duct in ICG group were higher than those in conventional group [(90.5% vs. 68.3%, 90.5% vs. 85.4%), P<0.05]. The amount of intraoperative blood loss, operation time, total dissection time of gallbladder triangle, postoperative hospitalization time and gastrointestinal function recovery time in ICG group were all shorter than those in conventional group (P<0.05). There was no significant difference in the rate of intraoperative bile duct injury and postoperative complications between the two groups (P>0.05).

ICG fluorescence imaging guided laparoscopic cholecystectomy can reduce immune damage, improve the exploration rate of common bile duct, hepatic duct and gallbladder duct, and reduce intraoperative blood loss.