This is a Da Vinci robot-assisted mesohepatectomy. First，the liver parenchyma was dissected along the falciform ligament to the middle hepatic vein. During the dissociation，the Glissonean pedicle of segment Ⅳ was ligated. Then，the right anterior hepatic pedicle was ligated along the Laennec capsule to mark the cutting line between the right anterior and posterior lobe. Finally，mesohepatectomy was completely performed after the middle hepatic vein was transsected and the right hepatic vein was exposed along the Laennec capsule. The operation duration was 225 mins with the blood loss of 30 ml. The liver parenchyma was dissected from the left lobe to the right lobe and from the foot side to the head side. The operation process was smooth with the stable surgical vision，clear anatomical identification and well protection of the inflow and outflow tract of the residual liver，which reflected the obvious technical advantages of the Da Vinci surgical robot system in complex liver resection.