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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2023, Vol. 17 ›› Issue (03): 300-304. doi: 10.3877/cma.j.issn.1674-3946.2023.03.018

• Original Article • Previous Articles     Next Articles

A comparative study of different digestive tract reconstruction schemes of complete laparoscopic total gastrectomy for esophagogastric junction cancer

Wenpeng Dai1, Weiming Qiu1, Keqiang Wang1, Laibin Luo1, Zhimin Xu1, Hunan Huang1, Helong Che1,()   

  1. 1. Department of General Surgery,No.908 Hospital of Joint Service Support Force of Chinese People’s Liberation Army,Yingtan Jiangxi Province 335000,China
  • Received:2022-06-17 Online:2023-06-26 Published:2023-06-02
  • Contact: Helong Che

Abstract:

Objective

To compare and analyze the clinical effects of different digestive tract reconstruction schemes in total laparoscopic gastrectomy(TLTG)for esophagogastric junction cancer(AEG).

Methods

A total of 126 patients with AEG who received TLTG treatment from January 2019 to May 2021 were selected as research objects,and the patients were divided into π shape group,Overlap group and double-channel group by random number table method,with 42 cases in each group. TLTG was performed in all the three groups. π shape group adopted π shape anastomosis,Overlap group adopted esophagojejunal preperistaltic lateral anastomosis(Overlap),double-channel group adopted double-channel jejunal interposition anastomosis. The data were processed by SPSS 22.0,and the measurement data of perioperative indicators were expressed by(

xˉ
±s). One-way ANOVA of variance was performed for comparison between multiple groups,LSD-t test was performed for comparison between two groups,and paired t test was performed for comparison within groups. The adoption rate(%)of counting data such as postoperative complications was indicated by Rank Sum test for rank counting data and χ2 test for non-rank counting data. P<0.05 indicated statistically significant difference.

Results

There was no significant difference in perioperative indexes among the three groups,such as operation time,intraoperative blood loss,number of lymph node dissection,anastomosis time,first exhaust time,first feeding time,getting out of bed time and postoperative hospitalization time(P>0.05). Postoperative complications occurred in all the three groups,and there was no statistical significance in the total incidence of postoperative complications among the three groups(P>0.05). However,the total incidence of postoperative complications in the dual-channel group was significantly lower than that in the π-shaped group(28.6% vs. 9.5%),and the difference was statistically significant (P<0.05. Six months after operation,nutritional indexes such as hemoglobin(Hb),total protein(TP),albumin(ALB)and body mass index(BMI)in the three groups were significantly decreased compared with those before operation (P<0.05,and nutritional indexes in the two-channel group were significantly higher than those in π shape group and Overlap group (P<0.05). Median follow-up time was 28 months. Kaplan-Meier analysis showed that cumulative overall survival(71.4% vs. 76.2% vs. 78.6%)and cumulative disease-free survival(69.0% vs. 73.8% vs. 76.2%)were compared among the three groups. There was no significant difference(Log-Rank χ2=1.007,1.058,P=0.604,0.589).

Conclusion

The three methods of digestive tract reconstruction in TLTG are safe and feasible,and the prognosis is similar. Double-channel jejunal interposition anastomosis can not only effectively reduce the occurrence of postoperative complications,but also be more conducive to postoperative nutritional recovery of patients,and its advantages are more obvious,which is worthy of clinical application.

Key words: Esophagogastric Junction, Adenocarcinoma, Total Laparoscopic, Gastrectomy, Digestive Tract Reconstruction

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