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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2023, Vol. 17 ›› Issue (01): 105-109. doi: 10.3877/cma.j.issn.1674-3946.2023.01.027

• Review • Previous Articles     Next Articles

Advances in fatty acid metabolism in cancer patients with cachexia

Yu Liu1, Meng Wang1,()   

  1. 1. Department of General Surgery,Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine,Nanjing Jiangsu Province 210008,China
  • Received:2022-04-13 Online:2023-02-26 Published:2023-01-05
  • Contact: Meng Wang

Abstract:

Cancer is expected to become the number one killer of human health. In recent years,there has been a surge in research on the nutritional metabolism of cancer,including the effects of nutrients such as glucose,amino acids,and fatty acids on the proliferation and spread of cancer. Cachexia is a key factor affecting the prognosis of cancer. About 80% of cancer patients suffer from cachexia,which leads to the failure of cancer treatment. At present,there are still many clinical studies on drug therapy and dietary therapy for cachexia. This review mainly reviews the research progress of cachexia fatty acid metabolism in gastric cancer through the effects of fatty acids on cancer cell proliferation and metastasis,cachexia fatty acid-related drugs,and dietary therapy.

Key words: Cachexia, Fatty Acid

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