To compare the feasibility and safety of two combined resection methods in the surgical treatment of adenocarcinoma of esophagogastric junction (AEG).

The clinical data of 89 patients with AEG from 2015 to 2017 were analyzed retrospectively. According to the type of operation, 42 cases were divided into the group A who underwent radical gastrectomy combined with pancreatic body and tail and splenectomy, while 47 cases were divided into the of group B who received radical gastrectomy combined with pancreatic wedge resection. Statistical analysis were performed by using SPSS 23.0 software. The measurement data with normally distributed such as gastrointestinal quality of life (GIQLI) and reflux disease questionnaire (RDQ) score were expressed as (±s), and were examined by using independent sample t test. The count data of complication and recurrence rate were expressed as percentage, and were examined by using χ² test. the survival was analyzed by log rank test. A P value of <0.05 was considered as statistically significant difference.

There was no significant difference between the group A and the group B in terms of the total incidence of postoperative complications (14.3% vs. 17.0%), the GIQLI and RDQ score on 3 months after operation, the recurrence and survival rate (P>0.05).

Both the gastrectomy combined with radical pancreatic tail and splenectomy and combined pancreatic wedge resection are feasible with similar postoperative complications and prognosis.