To investigate the accuracy of 3D reconstruction technique in preoperative anatomical classification of hilar cholangiocarcinoma (HCCA), and to explore the clinical application value of three-dimensional reconstruction combined with ICG imaging.

A total of 86 HCCA patients underwent surgical treatment from March 2017 to March 2020 were selected as the study subjects and were randomly divided into the combined group(43 cases) and the conventional group(43 cases), .The combined group was guided with the ICG imaging under the three-dimensional reconstruction model, while the conventional group was guided with the conventional imaging technique. Spss20.0 software were used to process the data. The perioperative indicators and other measurement data were expressed as (±s), and the comparison were analyzed by using independent t test; the postoperative complications and other count data were analyzed by using χ² test; K-M method were used for survival analysis; A P value of <0.05 was considered as statistically significant difference.

The accuracy of tumor typing diagnosis in the combined group was significantly higher than that in the conventional group (100% vs. 72.1%) P<0.05; The consistency rate of the combined group’s detection of pre-resection of the liver area compare with the actual surgical method was significantly higher than that in the conventional group (95.3% vs. 79.1%) P<0.05; There was no perioperative death both in the two groups. The operative time, hepatic Pringle block time and intraoperative bleeding in the combined group were better than those in the conventional group (P<0.05); The total incidence of postoperative complications in the combined group was significantly lower than that in the conventional group (13.9% vs. 37.2%) with significant differences (P<0.05). Follow-up of 3 to 51 months after operation, K-M curve analysis showed that there was no significant difference in terms of disease-free survival and cumulative overall survival rate between the two groups (P>0.05).

Three-dimensional reconstruction combined with ICG imaging could accurately evaluate HCCA before surgery, shorten the operative time, reduce intraoperative bleeding and could reduce the incidence of postoperative complications, which could be widely applied in clinical practice.