To compare the perioperative inflammatory factors and serum amylase levelsin laparoscopic surgery and laparotomy for acute cholecystitis.

From December 2015 to July 2017, 86 patients with acute cholecystitis were enrolled and randomly divided into two groups, including 43 cases in open group and 43 cases in laparoscopic group. Clinical data were analyzed by using SPSS18.0 software. Clinical efficacy and postoperative complications were examined by using chi-square test. Serum amylase and inflammatory factors were expressed as (±s) and examined by using independent t test. A valueof P < 0.05 was considered as statistically significant difference.

Clinical efficacy of 95.3% in laparoscopic group was significantly higher than 81.4% in open group (P <0.05). Compared with open group, there were less blood loss, shorter operation duration, exhaust duration, time of ambulation and hospital stay as well as less postoperative complications in the laparoscopic group (P<0.05). After surgery, serum amylase and inflammatory factors wereincreased at different levelin both groups, however much lower indicators were observed in the laparoscopic group than in open group (P<0.05).

For patients with acute cholecystitis, laparoscopicsurgery is recommended, with advantages such as minimal invasion, shorter recovery time and less complications. It is worthy of wider application and further popularization.