To explore the effect of different timing for laparoscopic cholecystectomy on the curative effect and rehabilitation of the elderly patients with acute cholecystitis.

Retrospective analysis was performed to select patients with acute cholecystitis who underwent laparoscopic cholecystectomy from September 2013 to September 2017. 59 patients who underwent surgery 48 hours after the onset of surgery were treated as an extension group, and the disease was implemented within 48 hours after onset. 59 patients underwent surgery as an early group.SPSS19.0 was used for statistical analysis. The indexes of postoperative operation, CD3⁺ and CD4⁺ were expressed as (±s) in both groups, and the independent t test was performed. The complication rates of two groups were tested by χ² test, P<0.05 was considered as the difference There is statistical significance.

The operation time, intraoperative blood loss, anal exhaust time and hospitalization time in the observation group were shorter than those in the control group (P<0.05). The CD3⁺ and CD4⁺ indexes of the observation group at 1, 2 and 4 days after operation (P<0.05). The incidences of perforation, infection, gangrene, intraperitoneal hemorrhage and bile duct injury in the early group were lower than those in the delayed group, with statistical significance (P<0.05).

Laparoscopic cholecystectomy in elderly patients with acute cholecystitis within 48 hours after the onset of the disease can effectively promote the recovery of the body, enhance the immune capacity and reduce the incidence of postoperative serious complications, which is worthy of promotion.