To explore the preventive effect of proximal splenic vein ligation during laparoscopic splenectomy on postoperative portal vein thrombosis.

The clinical data of 58 patients with portal hypertension who underwent surgical treatment from January 2022 to January 2025 were analyzed retrospectively. According to whether proximal splenic vein ligation was performed during the operation, the patients were divided into Group A (n=22, with intraoperative splenic vein ligation) and Group B (n=36, without intraoperative splenic vein ligation). Statistical software SPSS 22.0 was used for data analysis. Measurement data, such as perioperative indicators, were expressed as (±s) and analyzed by independent samples t test; count data, such as postoperative complications, were analyzed by χ² test. P<0.05 was considered statistically significant.

All patients in both groups successfully completed laparoscopic splenectomy, with no conversion to open surgery or deaths. In Group B, 1 patient developed bleeding due to pancreatic fistula after surgery and was cured and discharged after conservative treatment. The operation time in Group A was longer than that in Group B, while the number of cases with postoperative portal vein thrombosis in Group A was fewer than that in Group B (Note: There is a typo in the original text; B-ultrasound should be Group B), with statistically significant differences (both P<0.05). There were no statistically significant differences between the two groups in hospitalization costs, length of hospital stay, intraoperative blood loss, or postoperative pancreatic fistula (all P>0.05).

Proximal splenic vein ligation during laparoscopic splenectomy is safe and feasible, and can effectively prevent the formation of postoperative portal vein thrombosis.