Abstract:

With the changes in lifestyle habits and dietary structures in modern society, obesity has become a global disease, and its incidence rate is gradually increasing. Moreover, as a risk factor for the onset of many chronic diseases, obesity is closely related to the occurrence of type 2 diabetes mellitus (T2DM).Obesity often leads to a higher incidence of diabetes. Therefore, how to lose weight for the obese population has become a focal topic. Due to the corresponding limitations of conservative treatment, bariatric surgery has become an effective method for treating obesity and also has a definite therapeutic effect on T2DM. However,the applicability of each surgical procedure still has no clear conclusion. This article reviews a large number of clinical studies and explores the therapeutic effects of sleeve gastrectomy (SG), Roux-en-Y gastric bypass(RYGB), and one anastomosis gastric bypass (OAGB) on obesity complicated with T2DM. Through the review, it is found that all three surgical procedures can effectively reduce weight and significantly improve blood glucose levels after surgery. However, sleeve gastrectomy is inferior to gastric bypass surgery in terms of the therapeutic effect on improving diabetes. Therefore, when dealing with patients with obesity complicated with T2DM,gastric bypass surgery may be a better choice. Among gastric bypass surgeries, OAGB is more recommended by the author because it has only one anastomosis. Laparoscopic sleeve gastrectomy (LSG) has become the most widely performed bariatric surgical procedure globally due to its simple operation, without changing the original physiological anatomy of the gastrointestinal tract, and its definite therapeutic effect. It may be more suitable for patients with mild to moderate obesity and type 2 diabetes mellitus with a shorter disease course.

Key words: Obesity, Diabetes Mellitus, Type 2, Bariatric Surgery, Sleeve Gastrectomy, Gastric Bypass