Abstract:
Objective
To explore the effects of different approaches in endoscopic radical resection of thyroid cancer for patients with thyroid cancer.
Methods
The data of 115 patients who underwent endoscopic radical resection of thyroid cancer from January 2021 to December 2023 were retrospectively analyzed. 57 patients with the total areola approach were included in the total areola group, and 58 patients with the gasless axillary approach were included in the axillary group. All data were analyzed and processed using the SPSS 25.0 statistical software. Measurement data with a skewed distribution were described as［M(P25, P75)］, and the Mann-Whitney U test was used for data of different groups. Measurement data with a normal distribution were expressed as (
), an independent sample t test was used between groups, and a paired sample t test was used within groups; Enumeration data were expressed as［ cases (%)］, and the χ2 test was used, and the Rank Sum test was used for ranked data. P<0.05 was considered to indicate a statistically significant difference.
Results
There was no statistically significant difference in the number of lymph node dissections between the two groups (P>0.05); The operation time in the axillary group was shorter than that in the total areola group, and the postoperative drainage volume was less than that in the total areola group (P<0.05).Three days after the operation, the levels of blood calcium and parathyroid hormone (PTH) in the patients of the axillary group were higher than those in the total areola group, and the levels of serum tumor necrosis factor-α(TNF-α) and interleukin-6 (IL-6) were lower than those in the total areola group (P<0.05). The scores of the Numerical Rating Scale (NRS) and the Vancouver Scar Scale (VSS) of the patients in the axillary group were lower than those in the control group (P<0.05). The incidence of postoperative complications in the axillary group was lower than that in the total areola group (P<0.05), and there was no statistically significant difference in the recurrence rate between the groups (P>0.05).
Conclusion
Compared with the total areola approach,the gasless axillary approach in endoscopic radical resection of thyroid cancer has a shorter operation time and less postoperative drainage volume, causes mild stimulation to the function of the parathyroid gland, has better postoperative aesthetic appearance, and can reduce the occurrence of complications.
Key words:
Thyroid Neoplasms,
Thyroidectomy,
Endoscopy,
Surgical Approach,
Parathyroid Function
Xiaobei Wang, Qingfu Lv, Ting Ni. Clinical comparison of gasless axillary approach and total areola approach in endoscopic radical resection of thyroid cancer[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(04): 368-371.