Abstract:
Objective
To explore the efficacy and safety of colonoscopy-assisted endoscopic mucosal resection （EMR）， cold snare resection （CSP） and radiofrequency ablation （RFA） in the treatment of colorectal polyps ＜1cm in diameter.
Methods
A total of 297 patients with colorectal polyps admitted from January 2020 to January 2022 were prospectively selected and divided into EMR group （n=99 cases）， CSP group （n=99 cases） and RFA group （n=99 cases） according to random number table method.The three groups were treated with EMR， CSP and RFA， respectively.SPSS23.0 software was used to analyze the data and Rank Sum test was performed.The incidence of complications was measured by χ2 test， perioperative indexes and inflammatory indexes were expressed as （x± s）， t test was performed between two groups， and One-way ANOVA was performed between multiple groups.P＜0.05 was considered statistically significant.
Results
At 2 weeks after operation， there was no significant difference in total effective rate between CSP group and RFA group （P＞0.05）.The total effective rate of CSP group and RFA group was higher than EMR group （P＜0.05）.The intraoperative blood loss， operation time and 2d visual analogue VAS score in RFA and CSP groups were lower than those in EMR group （P＜0.05）.There was no significant difference between RFA group and CSP group （P＞0.05）.The 2d C-reactive protein （CRP） and interleukin-6 （IL-6） levels in RFA group and CSP group were lower than those in EMR group （P＜0.05）， but there was no significant difference between RFA group and CSP group （P＞0.05）.The total incidence of postoperative complications in CSP and RFA groups was lower than that in EMR group（P＜0.05）.The total incidence of postoperative complications in RFA group was lower than that in CSP group，but the difference was not statistically significant （P＞0.05）.
Conclusion
Compared with EMR， CSP and RFA have higher efficacy in the treatment of colorectal polyps ＜1cm in diameter， faster recovery of patients， lower levels of inflammatory factors， fewer complications， and higher safety.
Key words:
Colorectal Polyp,
Colonoscopy,
Endoscopic Mucosal Resection,
Cold Snare Polypectomy,
Radiofrequency Ablation
Jianbo Yang, Huan Ma, Xiaomei Huang, Huazhu Liu. Comparison of efficacy and safety of colonoscope-assisted EMR， CSP and RFA in the treatment of colorectal polyps ＜1cm in diameter[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(01): 76-79.