To investigate the safety and anti-reflux effects of piggyback interposition jejunal single channel reconstruction in esophagogastric junction adenocarcinoma（AEG）during laparoscopic proximal gastrectomy（LPG）.

Clinical data of 56 patients with AEG who received LPG from January 2020 to December 2022 were retrospectively analyzed，and they were divided into two-channel group（n=32）and single-channel group（n=24）according to different ways of digestive tract reconstruction. The two groups were treated with LPG. The two-channel group was treated with piggyback interposition jejunum double-channel reconstruction，and the single-channel group was treated with piggyback interposition jejunum single-channel reconstruction. SPSS 22.0 was used to analyze the data. Perioperative indicators，postoperative nutritional status and other measurement data were expressed by（

There were no significant differences in operation time，digestive tract reconstruction time，intraoperative blood loss，number of lymph node dissection，first exhaust time，postoperative hospital stay，recent postoperative complications，postoperative disturbance symptom grade，severity of RE and total score of Gerd Q between the two groups（P>0.05）. The incidence of postoperative reflux symptoms and reflux esophagitis in the single channel group was slightly lower than that in the double channel group（12.5%vs.18.8%，8.3%vs.12.5%），but the difference was not statistically significant（P>0.05）. Nutritional indexes such as albumin（ALB），hemoglobin（HB），total protein（TP）and body mass index（BMI）were significantly decreased in both groups 3 months after surgery（P<0.05），and nutritional indexes in the single channel group were significantly higher than those in the double channel group（P<0.05）.

Piggyback interposition jejunum single channel reconstruction in LPG is safe and feasible in AEG surgery. It not only achieves the same efficacy as double channel reconstruction，but also has the tendency to reduce postoperative reflux and is more beneficial to postoperative nutritional recovery of patients. It is a relatively ideal digestive tract reconstruction method and worthy of clinical application and promotion.