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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (06): 696-699. doi: 10.3877/cma.j.issn.1674-3946.2021.06.031

• Review • Previous Articles     Next Articles

Research progress on multi-stage mechanism of colorectal cancer liver metastasis

Dingchang Li1, Li Cao1, Peng Chen1, Guanglong Dong1,()   

  1. 1. Department of General Surgery, First Medical Center, General Hospital of PLA, Beijing 100853, China
  • Received:2021-02-07 Online:2021-12-26 Published:2022-01-20
  • Contact: Guanglong Dong
  • Supported by:
    National Natural Science Foundation of China(81773247)

Abstract:

Colorectal cancer is one of the common types malignant tumor types in China, of malignant tumors in my country, and many patients have already experienced liver metastasis when they are diagnosed, which is also the main reason for the high mortality rate of colorectal cancer. Therefore, it is important to study the mechanism of colorectal cancer liver metastasis (CLM). However, the specific mechanism of liver metastasis is not clearstill unclear at present. This article will review the mechanism of liver metastasis from the cellular and molecular level, hoping to explore new ideas and methods for the research and treatment of colorectal cancer liver metastasis.

Key words: Colorectal neoplasms, Liver metastasis, Molecular mechanism

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