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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (02): 157-161. doi: 10.3877/cma.j.issn.1674-3946.2021.02.012

Special Issue:

• Original Article • Previous Articles     Next Articles

Clinical analysis of anti-reflux gastric tube reconstruction in treating Siewert type Ⅱ and Ⅲ adenocarcinoma of esophagogastric junction

Dongliang Li1, Wei Wang2, Jiajie Zhou3, Feng Wang3, Guifan Tong3, Xu Ding1, Liuhua Wang2, Dong Tang2, Daorong Wang2,()   

  1. 1. Medical College of Yangzhou University, Yangzhou 225000, China
    2. Northern Jiangsu People's Hospital, Clinical Medical College of Yangzhou University, General Surgery Institute of Yangzhou, Yangzhou University, Yangzhou Clinical Medical School, Nanjing Medical University, Yangzhou Clinical Medical School, Dalian Medical University, Yangzhou 225000, China
    3. Dalian Medical University, Dalian 116044, China
  • Received:2020-06-04 Online:2021-04-26 Published:2021-04-25
  • Contact: Daorong Wang
  • Supported by:
    National Natural Science Foundation of China(81972269)

Abstract:

Objective

To analyze the clinical efficacy of laparoscopy-assisted proximal gastrectomy with anti-reflux gastric tube reconstruction for patients with Siewert type II and III adenocarcinoma of esophagogastric junction (AEG).

Methods

The clinical data of 59 patients with Siewert type II and III AEG, who underwent laparoscopy-assisted proximal gastrectomy from June 2017 to June 2019, was analyzed retrospectively. Among these patients, 30 patients in group A received traditional gastric tube reconstruction before July 2018, while 29 patients in group B underwent anti-reflux gastric tube reconstruction from June 2018 to June 2019. Statistical analysis were performed by using SPSS 19.0 software. Measurement data such as perioperative indicators and RDQ scores were expressed as (±s), and were examined by using independent t test. Postoperative gastroesophageal reflux symptoms, reflux esophagitis (RE), gastroesophageal reflux disease (GERD) and other count data were analyzed by using χ2 test. A P value of <0.05 was considered as statistically significant difference.

Results

There was no statistically significant difference in the incidence of gastroesophageal reflux symptoms, RE and GERD between the two groups (P>0.05). The RDQ score of group A were significantly higher than that of group B 3 months and 6months after the operation [(8.83±4.00) vs. (4.28±3.16), P<0.05], [(8.60±4.09) vs. (4.83±3.04), P<0.05].

Conclusion

Compared with the traditional gastric tube reconstruction, anti-reflux management could achieve better clinical outcome, with less medical cost and simple and safe operative procedures, which is worthy of clinical promotion.

Key words: Esophagogastric junction, Stomach neoplasms, Gastrectomy, Comparative effectiveness research, Adenocarcinoma of the esophagogastfic junction, Gastric tube

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