Research Progress in Metabolic Surgery on Obesity and Type 2 diabetes

doi:10.3877/cma.j.issn.1674-3946.2020.06.029

Abstract

Abstract:

Surgical treatment of obesity and type 2 diabetes is becoming one of the most effective treatments for metabolic diseases. In the field of surgery, a variety of metabolic surgical methods have emerged. Various weight-loss operations have improved obesity and its related metabolic complications. Obesity is related to many chronic diseases, such as type 2 diabetes, obstructive sleep apnea syndrome, hypertension, dyslipidemia cardiovascular diseases (myocardial infarction, stroke), non-alcoholic fatty liver disease(NAFLD), polycystic ovary syndrome, osteoarthritis, infertility, etc. Metabolic diseases are associated with obesity could be cured or significantly alleviated in the short term after bariatric surgery. However, the mechanism of this kind of operation is still not very clear. Various hypotheses, including the reduction of calorie intake after operation, the theory of foregut-hindgut, the change of serum bile acid and intestinal bacterial flora, could not fully explain different weight-loss operation methods could manage metabolic syndrome. However, we believe that in the future, with the support of a large number of clinical data studies and the research of the mechanism of action. In-depth study, we would get the exact answer and would benefit more patients.

Key words: Obesity, Diabetes mellitus, type 2, Metabolic surgery, Bariatric surgery, Mechanism study

Tao Fu, Weidong Jin. Research Progress in Metabolic Surgery on Obesity and Type 2 diabetes[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(06): 639-642.

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