Abstract:
Objective To explore the clinical effect of multiple measures combined with laparoscopic liver resection for patients with hepatocellular carcinoma complicated with cirrhosis and portal hypertension.
Methods The clinical data of 43 patients with liver cancer complicated with cirrhosis and portal hypertension, who received laparoscopic hepatectomy from January 2015 to July 2017, were retrospectively analyzed. Patients in the combined group (n=23) was given multiple measures combined laparoscopic hepatectomy, while patients in the conventional group (n=20) was given conventional laparoscopic hepatectomy. The postoperative follow-up of the patients ended up on July 2019. Statistical analysis were performed by using SPSS 22.0 software. Measurement data, such as Perioperative indicators were expressed as (±s), and were examined by using independent t test. postoperative complications were analyzed by using χ2 test A P value < 0.05 was considered as statistically significant difference.
Results The operation time, intraoperative blood loss, transfusion volume, gastrointestinal decompression time and hospital stay in the combined group were significantly lower than those in the conventional group respectively (P<0.05); Among 43 patients, 9 complications occurred within one week after surgery, and no liver failure occurred. The postoperative complication rate was 20.9% (3/23) in the multi-treatment group, which was lower than 30% (6/20) in the conventional group, with no significant difference (P>0.05). The recurrence and metastasis rate of the multi-method combination group was 46.5% (11/23), which was lower than 61.2% (12/20) in the conventional group. There was no significant difference in the disease-free survival rate between two groups until the observation end point (χ2=0.637, P=0.425).
Conclusion Multi-measurement combined with laparoscopic liver resection for the treatment of liver cancer with cirrhosis and portal hypertension is safe and feasible, with less intraoperative bleeding, shorter operation time, less complications, and lower postoperative recurrence rate.
Key words:
Liver neoplasms,
Liver cirrhosis,
Hypertension, portal,
Laparoscopes,
Hepatectomy
Shouhong Jia, Xu Lu, Bin Peng. Clinical application of multiple measures combined with laparoscopic liver resection for patients with hepatocellular carcinoma complicated with cirrhosis and portal hypertension[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2020, 14(06): 569-572.