To explore the incidence of cholangitis related to preoperative biliary drainage by PTCD or ERCP in patients with Ⅱ, Ⅲ, Ⅳ hepatic bile duct carcinoma.

A total of 90 patients needed preoperative biliary drainage with Ⅱ, Ⅲ, Ⅳ hepatic bile duct carcinoma treated in our hospital from January 2015 to March 2019 were selected. According to the different ways of reducing jaundice, they were divided into two groups, the ERCP groups(60 cases) and PTCD groups(30cases). SPSS24.0 software was used for analysis and processing. Measurement data such as liver function indicators were expressed as (±s), and compared with independent sample t test. The incidence of cholangitis and other statistical data were expressed as n(%), and compared with χ² test, P<0.05 being the test standard. P<0.05 was statistically significant.

Both ERCP group and PTBD group achieved the purpose of reducing jaundice, and there were significant differences in liver function indicators such as TBIL, ALP, gamma-gt and ALT levels between the two groups after preoperative biliary drainage (P<0.05). The incidence of drainage-related cholangitis in ERCP group was 33.3%, which was significant higher than that in PTBD group (13.3%, P<0.05). The incidence of drainage-related cholangitis in HCCA patients with type II was 5.3%, which was significantly lower than those in patients with type Ⅲ and Ⅳ (37.9% and 52.2%, P<0.05), but there was no significant difference between groups of patients with type Ⅲ and Ⅳ (P>0.05). There was no significant difference in the incidence of drainage-related cholangitis with type II between ERCP group and PTBD group (P>0.05), while the incidence of drainage-related cholangitis with type Ⅲ and Ⅲ、Ⅳ in ERCP group was significantly higher than those in PTBD group (P<0.05).

It is recommended for preoperative ERCP in HCCA patients with type II and PTCD in HCCA patients with type Ⅲ, Ⅳ.