To investigate the clinical effect and security of laparoscopic total mesopancreas excision in the treatment of pancreatic head carcinoma.

46 cases of pancreatic head carcinoma were collected from April 2013 to April 2016 in our hospital and conducted a retrospective analysis. According to the different surgical methods, the patients were divided into laparoscope group (25 cases) and open surgery group (21cases), the laparoscope group was given laparoscopic total mesopancreas excision surgery, the open surgery group was given open pancreaticoduodenectomy. Statistical analysis were performed by using SPSS 19.0 software, preoperative and postoperative related indicators were presented as and examined by using t test; enumeration data (excision rate of R0, the incidence of the complications after operation) was examined by chi square test. A P<0.05 was considered as significant difference.

The excision rate of R0 in laparoscope group was 88.0%, the excision rate of R0 in open surgery group was 61.9% (P<0.05). Compared with the open surgery group, the operation time of the laparoscope group was significantly increased, but the intraoperative blood loss and intraoperative transfusion were significantly decreased (P<0.05); Compared with the open surgery group, the postoperative anal exhaust time, eat liquid food time and hospital stays of the laparoscope group were significantly shortened (P<0.05). The incidence of postoperative complications of the laparoscope group was 16.0%, the incidence of postoperative complications of the open surgery group was 42.9%, the difference was statistically significant (P<0.05).

Laparoscopic total mesopancreas excision in the treatment of pancreatic head carcinoma has good clinical effect and security, it is worth promoting the application in clinic.